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1. Department of Nutrition, Tadulako University, Palu, Indonesia
The risk of degenerative diseases, including high blood pressure and high cholesterol levels, can occur at any age. This study aims to explore the relationship between several modifiable factors and blood pressure and cholesterol levels in adolescents. The survey was conducted in one of the Islamic schools in a densely populated area in Palu City using a cross-sectional study design with a simple random sampling technique on 100 respondents aged 15β18 years. Dietary and habitual intake as well as physical activity were collected through a 2x24-hour food recall questionnaire, a qualitative food frequency questionnaire, and an IPAQ questionnaire. Blood pressure and blood cholesterol levels were measured using a digital tension meter and easy touch GCU, respectively. Results indicated that 41 percent of adolescents had elevated blood pressure (>120/80 mmHg) and 42 percent had high cholesterol levels (β₯200 mg/dl), with an average systolic blood pressure of 121 mmHg and cholesterol levels of 199 mg/dL. Only sodium was significantly associated with blood pressure (p = 0.02), and no factors were significantly associated with cholesterol levels after multivariate analysis by including other variables: fat intake, potassium intake, fried and fast-food eating habits, physical activity, and gender (p > 0.05). Further exploration should include additional dietary factors such as saturated fat intake and overall dietary patterns, as well as psychosocial, and environmental influences to help design appropriate nutritional behavior change interventions for adolescents.
β’ Degenerative diseases such as high blood pressure and high cholesterol are currently found in adolescents, including in small cities like Palu.
β’ Sodium intake is significantly related to high blood pressure. However, no statistically proven factors are associated with cholesterol levels after multivariate analysis.
β’ Further research is needed to consider other confounding variables to design more appropriate nutritional behavior change interventions for adolescents
Adolescence is a stage of life that represent a phase of peak growth. During this period, there are several changes happened in body composition, including significant increase in weight and bone mass, along with high level of physical activity, which lead to the changes in nutritional needs during late adolescence (1). At this period, nutritional problem often arises. The imbalance between nutrient intake and need able to trigger various nutritional problem in adolescents (2β4). High cholesterol level and increased blood pressure are nutrition-related health issues which its prevalence is rising among adolescents in Indonesia (5, 6).
The global prevalence of hypercholesterolemia reached around 30-40%, indicating that nearly half of the world population experiencing high cholesterol level (7β10). In Indonesia, the prevalence of hypercholesterolemia aged more than 15 years old reached around 30 percent, with the prevalence of very high cholesterol level among adolescents aged 15-24 years old reached 10 percent (5). Several nutrition and health surveys among adolescents showed that the percentage of adolescents with high total cholesterol level reaching 50% (11, 12).
The prevalence of high blood pressure also shows a high number. In 2019, the global prevalence of hypertension was 33.1 percent (13). Hypertension in Southeast Asia was 33.1 percent, where in Indonesia the prevalence is 32.4 percent (13). Although this number decreased in 2023, the prevalence of hypertension in individual aged β₯18 years still above 30 percent (14). Among adolescents aged 15-19 years, the prevalence of adolescents with elevated and classified as high blood pressure were 19.4 percent (15). This prevalence has increased from previous year where the number only 8.4% (6).
High cholesterol level and high blood pressure are among non-communicable diseases associated with modifiable and non-modifiable factors (16). Some modifiable factors have relation to high cholesterol level and high blood pressure include unhealthy diet and low physical activity (17, 18). High sodium intake, low potassium, and high fat, including eating junk food and fried foods, are associated with high blood pressure and cholesterol (19β21).
Religion-based education is associated with health behaviors, including eating patterns, stress management, and adolescents' psychological well-being (22, 23). In Islamic school, students are instilled with Islamic values, such as halal and good food, avoiding excess, and maintaining trust regarding their body as a gift from God (24). However, various studies have found that some principles are often not implemented in good practices (25, 26), This may be related to the influence of the modern environment, which includes the availability and affordability of fast food and attractive processed snacks, which have a stronger influence on adolescents' eating preferences than recommended eating guidelines (27).Studying adolescent health in Islamic schools provides important insights into how faith-based education contributes to eating behaviors and adolescent health outcomes (28)
This research aims to identify modifiable factors related to cholesterol level and blood pressure among adolescents at Islamic school in Palu, Indonesia. Exploring factors related to high cholesterol and blood pressure among adolescents studying in Islamic school is particularly important since lifestyle patterns, dietary habits, and physical activity levels in Islamic school settings may differ from general populations, providing a quicker opportunity to improve their health condition before leading to worser health outcomes.
This research is an observational analytic descriptive study with cross-sectional design conducted at one of the Islam senior high schools in a densely populated area in Palu City from August to September 2024. The method of respondent selection in this study was a simple random sampling technique with a sample size of 100 respondents, which was determined based on the Lemeshow formula for sample size calculation (29). The respondents were student attending school at research location with inclusion criteria of being 15-17 years old, not currently consuming medication that affecting blood pressure and cholesterol level, willing and obtaining permission from their parents or guardian. Respondents were excluded if they were on a special diet prescribed by a doctor, were ill, or did not finishing the data collection. By these criteria, there were no respondents excluded in this study.
Data on fat (grams), sodium (milligrams), and potassium (milligrams) intake were collected through two non-consecutive 24-hour dietary recalls. Information on fast and fried food consumption habits was collected through a Food Frequency Questionnaire (FFQ) that was pre-tested among adolescents from a population with characteristics similar to those of the study participants to ensure cultural and contextual relevance. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ). The blood pressure measurement procedure followed the Indonesia Health Survey protocol of the Indonesian Ministry of Health, using a digital sphygmomanometer (30). Total cholesterol levels were measured from fingertip capillary blood using an Easy Touch GCU without fasting.
Fast food and fried food eating habits are categorized as never, rarely (<3 times/month), sometimes (1-2 times/week), often (1 time/day), and very often (>1 time/day) (5). Physical activity consisted of light (<600 MET-minutes/week), moderate (β₯600 MET-minutes/week), and vigorous (β₯1500 MET-minutes/week) (31). Respondents are categorized as having high blood pressure if their blood pressure is elevated or high (systolic blood pressure >120 mmHg) and having high cholesterol if their total cholesterol level is greater than or equal to 200 mg/dL. The relationship between variables was identified using Spearman-Rho test at 95% confidence level. Logistic regression was used to determine the simultaneous relationship between variables concerning adolescentsβ cholesterol level and blood pressure.
CODE OF HEALTH ETHICS
This study has met ethical eligibility based on the ethical clearance certificate issued by the Health Research Ethics Committee of the Faculty of Medicine, Tadulako University, Number: 6925/UN28.10/KL/2024
A total of 100 respondents participated in the study. Most respondents were girls (60%), with the majority being 16 years old (52%) (Table 1).
Table 1. The characteristics of respondents
Variable | n | % |
Gender | ||
Male | 40 | 40 |
Female | 60 | 60 |
Age (years) | ||
15 | 25 | 25 |
16 | 52 | 52 |
17 | 23 | 23 |
More than 50 percent of respondents have fat intake exceeding the Recommended Dietary Allowances (RDAs), which are 85 grams per day for men and 70 grams per day for women. Most respondents also have sodium intake exceeding 1700 mg/day (65%), while 64% have potassium intake below RDA (>5,300 mg/day) (Table 2). The average fat intake of respondents is 80 grams for both men and women. Sodium and potassium intake are 1967 mg and 1126 mg, respectively.
Table 2. The Distribution of Fat, Natrium, and Potassium Intake of Respondents
Variable | n | % |
|---|---|---|
Fat Intake | ||
Excess Intake (male >85 g/day; female >70 g/day) | 51 | 51 |
Sufficient intake (male 85 g/day; female 70 g/day) | 49 | 49 |
Natrium Intake | ||
Excess Intake (>1700 mg/day) | 65 | 65 |
Sufficient intake (β€1700 g/day) | 35 | 35 |
Potassium Intake | ||
Excess Intake (<5.300 mg/day) | 64 | 64 |
Sufficient intake (5.300 mg/day) | 36 | 36 |
Regarding eating habits, 60% of respondents rarely consumed junk food (less than 3 times per month), while 41% reported eating fried foods at least once a day. Most respondents (61%) had moderate physical activity levels (Table 3).
Table 3. The Distribution of Junk Food and Fried Food Habitual Intake and Physical Activity of Respondents
Variable | n | % |
Junk Food Habitual Intake | ||
Never | 4 | 4 |
Rarely | 60 | 60 |
Sometimes | 34 | 34 |
Often | 1 | 1 |
Very often | 1 | 1 |
Fried Food Habitual Intake | ||
Never | 1 | 1 |
Rarely | 14 | 14 |
Sometimes | 30 | 30 |
Often | 41 | 41 |
Very often | 14 | 14 |
Physical Activity | ||
Light | 4 | 4 |
Moderate | 61 | 61 |
Vigorous | 35 | 35 |
This studyβs results indicate that most adolescents (59%) have blood pressure above normal, with an average systolic blood pressure of 121 mmHg and a maximum of 163 mmHg (Table 4). The percentage of adolescents with a total cholesterol level also shows a high number. Over 40% of adolescents have total cholesterol levels above 200 mg/dL.
Analysis of several modifiable factors examined in this study shows that only habitual intake of junk food is significantly associated with blood pressure in adolescents (p=0.04) with a negative correlation (Table 5). This means the more frequently junk food is consumed, the lower the blood pressure in adolescents.
Table 4 Blood Pressure And Cholesterol Level of Respondents
Variable | n | % | Mean (Min -Max) |
Blood Pressure | |||
High | 59 | 59 | |
Normal | 41 | 41 | |
Cholesterol Level | |||
High | 42 | 42 | |
Normal | 58 | 58 | |
Table 5 Blood pressure and cholesterol association with several modifiable factors
Blood Pressure/ Cholesterol | Variables | Spearman Correlation Coefficient | p-value |
|---|---|---|---|
Blood Pressure | Fat Intake | -0,09 | 0.33 |
Sodium intake | 0.16 | 0.12 | |
Potassium intake | 0.09 | 0.18 | |
Fried food habitual intake | -0.11 | 0.23 | |
Junk food habitual intake | -0.20 | 0.04* | |
Physical activity | -0.17 | 0.09 | |
Cholesterol level | -0.11 | 0.95 | |
Gender | -0.08 | 0.41 | |
Cholesterol | Fat Intake | -0.05 | 0.62 |
Fried Food eating habit | 0.05 | 0.64 | |
Junk Food eating habit | -0.02 | 0.85 | |
Physical Activity | 0.13 | 0.19 | |
Gender | -0.09 | 0.38 |
*p-value < 0.05
The relationship between habitual junk food intake and blood pressure faded after simultaneously including all other variables (Table 6). Sodium intake became significantly associated with blood pressure in adolescents. This means the higher the sodium intake, the higher the blood pressure.
Table 6. Multivariate analysis of Blood pressure and cholesterol with several modifiable factors
Variables | B | p-value |
|---|---|---|
Blood Pressure | ||
Fat Intake | -0.01 | 0.42 |
Sodium intake | 1.28 | 0.02* |
Potassium intake | 0.57 | 0.44 |
Fried food habitual intake | -0.36 | 0.23 |
Junk food eating habit | -0.47 | 0.35 |
Physical activity | -0.59 | 0.25 |
Cholesterol level | -0.00 | 0.44 |
Gender | -0.16 | 0.74 |
Constant | 0.91 | 0.69 |
Cholesterol Level | ||
Fat Intake | -0.01 | 0.55 |
Fried Food eating habit | 0.31 | 0.27 |
Junk Food eating habit | 0.30 | 0.50 |
Physical Activity | -0.65 | 0.18 |
Gender | 0.20 | 0.65 |
Constant | -0.78 | 0.60 |
*p-value < 0.05.
This study explored modifiable factors associated with blood pressure and cholesterol levels among adolescents in an Islamic school in Palu City. The findings reveal a concerning prevalence of elevated blood pressure (59%) and high cholesterol (42%) among adolescents, indicating an emerging risk of non-communicable diseases at an early age.
The prevalence of adolescents with increased and high blood pressure in this study was found to be higher compared to several other studies in Indonesia and other parts of the world (15, 32, 33). Adolescents' average systolic blood pressure was also exceeded the average values observed in others studies, ranging from 108 - 113 mmHg (33β35).
Similarly, the proportion of adolescents with total cholesterol levels above 200 mg/dL in this study was slightly higher than the national statistic for Indonesians aged 13β34 years, which reported a prevalence of 39.4% (14). The mean cholesterol level among respondents was 199 mg/dL, which falls within the borderline between normal and high categories. The maximum cholesterol level among adolescents reaches 290 mg/dL, which categorized as very high.
Overall, the prevalence of adolescents with high cholesterol in this study was greater than that reported in previous studies in Indonesia and several systematic studies in other countries (15, 36, 37). Two studies showed higher figures than this research (11, 12). However, one of these studies used a lower cut-off point for defining high cholesterol (170 mg/dL) (11), while the other focused on slightly older adolescents, aged 18-24 years (12), which may explain difference.
This study found that more than half of the adolescents had fat and sodium intakes exceeding the Recommended Dietary Allowances (RDA), while most had inadequate potassium intake. The percentage of adolescents with fat intake exceeding RDA in this study is lower compared to other studies in Indonesia (38). However, fat intake in this study was higher than intake of younger adolescents (13-15 years) in Sumatra (39) or several other studies with adolescent group aged 15-17 years in Java (40, 41). For average intake of fat, this study shows lower value compared to adolescent intake in Indonesia in 2010 (42) but much higher than the average fat intake among adolescent girls in rural Indonesia or other countries (43, 44).
The average sodium intake of adolescents in this study was also lower than several other countries (45, 46). However, this average indicates that the adolescents' intake in this study was higher than the RDA (47). On the contrary, the average potassium intake was much lower than Indonesian adolescent RDA (47). This trend is identical to several studies in other region of Indonesia, Mexico, and the United States (48β50).
In eating habits, it is known that most respondents rarely consuming junk food or consuming junk food less than 3 times per month (60%). This is in contrast to the habit of eating fried foods frequently, where almost half of respondents (41%) eat at least 1 time a day. The habit of eating fried foods frequently among adolescents was found in various regions of Indonesia (51). Cooking food by frying is Indonesia's most popular food preparation method. Fried foods provide a more savory and crispy sensation, which most Indonesians prefer (27, 52).
This study mainly classified adolescents' physical activity as moderate (61%). Several studies showed lower physical activity level among urban adolescents compare to rural adolescents (53β55). Adolescents have longer screen time compare to other age group, especially after school (56, 57). This research is located in a densely populated area near traditional market center in the city of Palu. Most of the residents in this area work as entrepreneur, including seller (58). This condition allows adolescents to help their parents, who are entrepreneur, in the selling process.
Analysis of several modifiable factors examined in this study shows that only habitual intake of junk food is significantly associated with blood pressure in adolescents (p=0.04) with a negative correlation. This means the more frequently junk food is consumed, the lower the blood pressure in adolescents. This counterintuitive result may be explained by several factors. First, adolescents with higher junk food consumption may also have higher overall energy expenditure or physical activity levels, which could mitigate the impact of unhealthy diets on blood pressure (59). Second, there is a possibility of underreporting bias, where participants with higher blood pressure underreported their junk food consumption due to social desirability or recall limitations (60). Third, metabolic differences and short-term dietary effects in adolescents might not immediately reflect long-term consequences of unhealthy eating habits, leading to misleading associations (61). However, since this relationship disappeared in the multivariate analysis, it is likely that the initial correlation was confounded by other factors such as sodium intake or physical activity levels, rather than representing a true association . Sodium intake became significantly associated with blood pressure in adolescents. This means the higher the sodium intake, the higher the blood pressure.
High sodium level is associated with high blood pressure, the result is the same as found in various cohort studies (62). Sodium plays a role in maintaining water stability and controlling blood pressure (63). High sodium levels in bloodstream can lead to water retention, ultimately increasing blood volume and boosting blood circulation, making the heart works harder to distribute blood (64). Excessive sodium intake can also impacting the enlargement of artery size, leading to increment of blood pressure (65).
In contrast, other dietary factors such as fat and potassium intake, as well as fried and fast-food consumption, were not significantly associated with blood pressure. This may be due to the relatively narrow variation of intake within the study population, measurement limitations from short-term dietary recall, or the buffering effects of other unmeasured factors such as total energy expenditure, genetic predisposition, and psychosocial stress (66, 67). Moreover, the cross-sectional design limits the ability to detect long-term cumulative effects of these factors. Therefore, while sodium emerged as a key determinant in this population, future longitudinal studies are needed to explore the combined effects of multiple dietary and lifestyle factors on adolescent blood pressure.
Several modifiable factors identified in this study were not associated with adolescent cholesterol level. Various other factors that were not studied, such as intake of saturated fats and trans fats, especially those derived from packaged foods, are variables that might explain the relationship between modifiable factors and cholesterol level (68, 69). Although attempts were made to include several non-modifiable factors in this study, other aspects such as genetics, race, and ethnicity were not explored, potentially obscuring the relationship between variables (70, 71).
This research presents important information related to non-communicable diseases among adolescents, which is crucial for the prevention efforts against larger health issues that may arise. This research also fills the information gap, especially in Islamic schools that are rarely targeted, thus providing specific recommendations for religious-based schools (72). Several other factors related to blood pressure and cholesterol among adolescents were not identified in this study, which could obscure the relationships between variables examined in this research. Cross-sectional research design also does not allow researchers to explain the relationship found as cause and effect
About two-fifths of adolescents experienced blood pressure and cholesterol level above normal. The modifiable factor related to blood pressure is sodium intake. High sodium intake is associated with high blood pressure. Other factors, including mediator of behavioral changes related to blood pressure and cholesterol level, must be explored to develop an appropriate intervention model to prevent increasing blood pressure and cholesterol level among adolescents, especially those who attending Islamic or other religious schools
An artificial intelligence tool (Grammarly) was used solely for language editing and grammar correction during the preparation of this manuscript. The authors reviewed, verified, and approved all content after AI-assisted editing and take full responsibility for the accuracy, integrity, and final content of the manuscript
This research received no external funding
The authors thank the Head and teachers of Palu State Islamic High School for permission and facilitating the data collection process
The authors declare no conflict of interest
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